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Retin-A (tretinoin) cream is a topical form of vitamin A. It reduces the formation of pimples and promotes quick healing of pimples that do develop, especially in the case of blackheads, pimples and papules. Retin-A cream use in pregnancy and breast-feeding: There have been isolated reports of birth defects among babies born to women exposed to topical tretinoin during pregnancy. To date, there have been no adequate and well-controlled prospective studies performed in pregnant women and this teratogenic blood level of tretinoin is not known. However, a well-conducted retrospective cohort study of babies born to women exposed to topical tretinoin during the 1st trimester of pregnancy found no excess birth defects among these babies when compared with babies born to women in the same cohort who were not similarly exposed. Topical tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether tretinoin is excreted in human milk. Since many drugs are excreted in human milk, caution should be exercised when Retin-A is administered to a nursing mother. Retin-A cream is contraindicated in patients with: - A history of sensitivity/hypersensitivity reactions to any of the components The skin of certain sensitive individuals may become excessively red, swollen, bulered or crusted. If you are experiencing severe or persistent irritation, discontinue the use of Retin-A cream and consult your physician. There have been reports that, in some patients, areas treated with Retina-A cream developed a temporary increase or decrease in the amount of skin pigment (color) present. The pigment in these areas returned to normal either when the skin was allowed to adjust to Retin-A cream or therapy was discontinued. |
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