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Benefits of Nexium (esomeprazole): * For people who suffer from the pain and burning associated with acid reflux and GERD, relief is the most important benefit of taking Nexium. Just one convenient dose controls acid for up to 24 hours, and there is no need to avoid food or beverages. Four multicenter, double-blind, randomized trials evaluated the healing rates of Nexium 40 mg, Nexium 20 mg, and omeprazole 20 mg in subjects with endoscopically diagnosed erosive esophagitis. Healing rates were evaluated at week four and eight. At week eight, healing rates were higher with Nexium treatment compared to omeprazole in all four studies. Nexium's effectiveness in the resolution of GERD (Gastroesophageal Reflux Disease) symptoms was evaluated in two multicenter, randomized, double-blind, placebo-controlled trials. These trials were conducted in a total of 717 subjects, and they compared four weeks of treatment with Nexium 20 mg or 40 mg once daily versus placebo. The percentage of subjects who were symptom-free of heartburn was significantly higher in the Nexium groups compared to placebo at all follow-up visits (weeks 1, 2 and 4). |
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