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Medicine profilesNexium (esomeprazole magnesium) drug profile

Nexium (esomeprazole magnesium) drug profile

Chemical Name: Esomeprazole
Generic Names: Esomeprazole Sodium, Esomperazole, Esomeprazole
Substance: Esomeprazole magnesium

Common brand, trade, commercial denominations: Nexium, Sompraz, Zoleri, Lucen, Esopral, Axagon, Nexiam, Nexium I.V.

Manufacturers: AstraZeneca Pharmaceuticals, Sun Pharmaceuticals, Bracco.

Systematic (IUPAC) name: (S)-5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
Molecular formula: C17H19N3O3S
Molecular mass: 345.417 g/mol
Bioavailability: 50 to 90%
Half life: 1–1.5 hours
Excretion: 80% renal, 20% faecal
Protein Binding: 97%
Absorption: 90%

CAS number: 119141-88-7
Drug Category: Antihistamines, Enzyme Inhibitors
Pharmacologic class: Proton pump inhibitor
Therapeutic class: Antiulcer agent
Routes: oral, IV (intravenous)
Products related to this article:
Nexium
Nexium

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