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Cytomel is a brand name of the generic drug Liothyronine, which is a synthetic form of the T3 thyroid hormone. Liothyronine is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used to help decrease the size of enlarged thyroid glands (known as goiter). Contraindications Thyroid hormone preparations are generally contraindicated in patients with diagnosed but as yet uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis and apparent hypersensitivity to any of their active or extraneous constituents. There is no well-documented evidence from the literature however, of true allergic or idiosyncratic reactions to thyroid hormone. Dietary considerations Cytomel contains lactose as a filler. When taking both synthetic T4 and T3 as separate pills, the ratio of T3 to T4 can be controlled. However, the absorption of T4 is so variable (from 40 to 72 percent) that the ratio cannot be said to be constant. Occasionally, T3 is used as a treatment in itself. For many patients, taking T3 in addition to T4 has relieved the symptoms of hypothyroidism that wouldn't disappear on T4 alone. A large body of research supports the use of T3 in addition to T4 for hypothyroid patients. Other disadvantage is that T3 is faster-acting than T4, so patients sometimes spread out their dose and take it two or more times a day to avoid having their energy levels crash when the effects of T3 wear off. Although lab results may not indicate a problem, even a combination of synthetic T4 and T3 sometimes doesn't alleviate all of the symptoms of hypothyroidism. Pure T3 cannot be used by itself during a pregnancy. Much of the pregnancy fetus depends on a good supply of T4. Those taking synthetic T3 with T4 need to take two types of pills and have two prescriptions filled instead of just one. Thyroid hormone should not be used to treat obesity in patients with normal thyroid function. Liothyronine is ineffective for weight reduction in normal thyroid patients and may cause serious or life-threatening toxicity, especially when taken with amphetamines. Talk to your doctor about the potential risks associated with this medication. |
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