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Celebrex (celecoxib) drug profile

Pharmaceutical (Substance) Name: Celecoxib

Common Brand/Trade/Commercial denominations: Celebrex, Celebra, Cobix, Celcoxx, Selecap

Manufacturers: Pfizer, Pharmacia Corp., Alfa Chem, Tecoland Corporation, Henan Sunny Industry Co., Ltd. and others

Systematic (IUPAC) name: 4-[5-(4-methylphenyl)-3-(trifluoromethyl) pyrazol-1-yl]benzenesulfonamide
CAS number: 169590-42-5
ATC code: L01XX33 M01AH01

Molecular formula: C17H14F3N3O2S
Molecular weight: 381.373 g/mol

Bioavailability: 40%
Protein binding: 97% (mainly to serum albumin)
Active (Half) Life: ~11 hours
Excretion: Renal 27%, faecal 57%

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