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The studies were designed with all participants eating a reduced-calorie diet for 4 weeks, followed by the diet plus Xenical or the diet alone for 52 weeks. After 52 weeks, those taking Xenical plus diet lost an average of twice as much weight as those who used the diet alone (approximately 13.4 lbs versus 5.8 lbs). Furthermore, 69.1% of patients receiving Xenical lost 3% of their total body weight (an average of 13 lbs) after 3 months and 19 lbs after 1 year.
There is clear scientific evidence that if you are overweight, losing as little as 5% to 10% of your body weight can result in improved health. In studies of Xenical, almost two thirds of people treated with Xenical plus diet successfully lost at least 5% of their body weight after 2 years. In comparison, only half of the people treated with diet alone managed to lose 5% of their weight.
Weight loss with Xenical and a healthy diet also improves a number of weight-related health risks. Studies show that weight loss with Xenical can:
- Decrease total and LDL cholesterol (level of low-density lipoprotein-also known as bad cholesterol)
- Improve ratio of bad to good cholesterol (LDL/HDL cholesterol)
- Reduce blood pressure
- Reduce levels of insulin (hormone that allows glucose or sugar to enter the body's cells), high levels of which are associated with coronary heart disease
- Reduce the risk or delay the progression to type 2 diabetes in patients
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