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Medicine profilesPlavix (clopidogrel) drug profile

Plavix (clopidogrel) drug profile

Pharmaceutical name: Clopidogrel bisulfate
Substance: Clopidogrel [Ban:Inn]
Active ingredient: Clopidogrel hydrogen sulphate

Common brand, trade, commercial denominations: Plavix, Clopilet, Ceruvin, Iscover, Cloplat-75.

Manufacturers: Bristol-Myers Squibb, Sanofi-Aventis, Sun Pharmaceuticals, Ranbaxy Laboratories, Apotex Corp, Allscripts Healthcare Solutions, Cipla, Teva.

Systematic (IUPAC) name: (+)-(S)-methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
Molecular formula: C16H16ClNO2S
Molecular mass: 419.9 g/mol
Bioavailability: >50%
Protein binding: 94–98%
Half life: 7–8 hours (inactive metabolite)
Excretion: 50% renal, 46% biliary

CAS number: 113665-84-2
Pharmacologic class: platelet aggregation inhibitor
Therapeutic class: antiplatelet drug
Routes: oral
Products related to this article:
Plavix
Plavix

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